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Before she became Jean Grey in X-Men, Famke Janssen played Miss Burke, a well-intentioned high school teacher who is utterly unable to handle Josh Hartnett's bad boy charisma.
What's the Best MCU Show? Of all Sil's victims, this is the one you don't feel the least bit bad for.
Dan Aykroyd's character in My Stepmother is an Alien is a notable exception.